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PreviewIssue DateTitleAuthor(s)
2008The IL-3/IL-5/GM-CSF common beta receptor plays a pivotal role in the regulation of Th2 immunity and allergic airway inflammationAsquith, K.; Ramshaw, H.; Hansbro, P.; Beagley, K.; Lopez, A.; Foster, P.
2010Cutting edge: Basophils are transiently recruited into the draining lymph nodes during Helminth infection via IL-3, but infection-induced Th2 immunity can develop without Basophil lymph node recruitment or IL-3Kim, S.; Prout, M.; Ramshaw, H.; Lopez, A.; LeGros, G.; Min, B.
2014Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cellsNievergall, E.; Ramshaw, H.; Yong, A.; Biondo, M.; Busfield, S.; Vairo, G.; Lopez, A.; Hughes, T.; White, D.; Hiwase, D.
2015Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient miceLee, E.; Yee, D.; Busfield, S.; McManus, J.; Cummings, N.; Vairo, G.; Wei, A.; Ramshaw, H.; Powell, J.; Lopez, A.; Lewis, I.; McCall, M.; Lock, R.
200914-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survivalBarry, E.; Felquer, F.; Powell, J.; Biggs, L.; Stomski, F.; Urbani, A.; Ramshaw, H.; Hoffmann, P.; Wilce, M.; Grimbaldeston, M.; Lopez, A.; Guthridge, M.
2007The Shc-binding site of the β[c] subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesisRamshaw, H.; Guthridge, M.; Stomski, F.; Barry, E.; Ooms, L.; Mitchell, C.; Begley, C.; Lopez, A.
2009Sphingosine kinase regulates the rate of endothelial progenitor cell differentiationBonder, C.; Sun, W.; Matthews, T.; Cassano, C.; Li, X.; Ramshaw, H.; Pitson, S.; Lopez, A.; Coates, P.; Proia, R.; Vadas, M.; Gamble, J.
2004The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kB and induction of bcl-2Guthridge, M.; Barry, E.; Felquer, F.; Mc Clure, B.; Stomski, F.; Ramshaw, H.; Lopez, A.
2012Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsetsMarkey, K.; Koyama, M.; Kuns, R.; Lineburg, K.; Wilson, Y.; Olver, S.; Raffelt, N.; Don, A.; Varelias, A.; Robb, R.; Cheong, M.; Engwerda, C.; Steptoe, R.; Ramshaw, H.; Lopez, A.; Vega-Ramos, J.; Lew, A.; Villadangos, J.; Hill, G.; MacDonald, K.
2002The development of cytokine receptor antagonists as potential therapeutic agents for the myeloproliferative disordersRamshaw, H.; Lopez, A.; Bardy, P.