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PreviewIssue DateTitleAuthor(s)
2014Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cellsNievergall, E.; Ramshaw, H.; Yong, A.; Biondo, M.; Busfield, S.; Vairo, G.; Lopez, A.; Hughes, T.; White, D.; Hiwase, D.
2015Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient miceLee, E.; Yee, D.; Busfield, S.; McManus, J.; Cummings, N.; Vairo, G.; Wei, A.; Ramshaw, H.; Powell, J.; Lopez, A.; Lewis, I.; McCall, M.; Lock, R.
200914-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survivalBarry, E.; Felquer, F.; Powell, J.; Biggs, L.; Stomski, F.; Urbani, A.; Ramshaw, H.; Hoffmann, P.; Wilce, M.; Grimbaldeston, M.; Lopez, A.; Guthridge, M.
2007The Shc-binding site of the β[c] subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesisRamshaw, H.; Guthridge, M.; Stomski, F.; Barry, E.; Ooms, L.; Mitchell, C.; Begley, C.; Lopez, A.
2004The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kB and induction of bcl-2Guthridge, M.; Barry, E.; Felquer, F.; Mc Clure, B.; Stomski, F.; Ramshaw, H.; Lopez, A.
2002The development of cytokine receptor antagonists as potential therapeutic agents for the myeloproliferative disordersRamshaw, H.; Lopez, A.; Bardy, P.
2017Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.Powell, J.; Lewis, A.; Zhu, W.; Toubia, J.; Pitman, M.; Wallington-Beddoe, C.; Moretti, P.; Iarossi, D.; Samaraweera, S.; Cummings, N.; Ramshaw, H.; Thomas, D.; Wei, A.; Lopez, A.; D'Andrea, R.; Lewis, I.; Pitson, S.
2002Chronic myelomonocytic leukemia requires granulocyte-macrophage colony-stimulating factor for growth in vitro and in vivoRamshaw, H.; Bardy, P.; Lee, M.; Lopez, A.