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Results 151-160 of 171 (Search time: 0.003 seconds).
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PreviewIssue DateTitleAuthor(s)
2012Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity TrialGuilhot, F.; Hughes, T.; Cortes, J.; Druker, B.; Baccarani, M.; Gathmann, I.; Hayes, M.; Granvil, C.; Wang, Y.
2012Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to high-dose imatinib achieve better responses and have lower failure rates than those randomized to standard-dose imatinibWhite, D.; Radich, J.; Soverini, S.; Saunders, V.; Frede, A.; Dang, P.; Cilloni, D.; Lin, P.; Mongay, L.; Woodman, R.; Manley, P.; Slader, C.; Kim, D.; Pane, F.; Martinelli, G.; Saglio, G.; Hughes, T.
2013Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2Eadie, L.; Saunders, V.; Hughes, T.; White, D.
2011Tyrosine kinase inhibitor resistance in chronic myeloid leukemia cell lines: investigating resistance pathwaysTang, C.; Schafranek, L.; Watkins, D.; Parker, W.; Moore, S.; Prime, J.; White, D.; Hughes, T.
2016ABCB1 Overexpression Is a key initiator of resistance to tyrosine kinase inhibitors in CML cell linesEadie, L.; Hughes, T.; White, D.; Eaves, C.
2009Measuring minimal residual disease in chronic myeloid leukemia: Fluorescence in situ hybridization and polymerase chain reactionHughes, T.; Branford, S.
2010Dasatinib alters the metastatic phenotype of B16-OVA melanoma in vivoFraser, C.; Lousberg, E.; Guerin, L.; Hughes, T.; Brown, M.; Diener, K.; Hayball, J.
2005Inhibition of c-fms by imatinib - Expanding the spectrum of treatmentDewar, A.; Zannettino, A.; Hughes, T.; Lyons, A.
2015Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemiaSchafranek, L.; Nievergall, E.; Powell, J.; Hiwase, D.; Leclercq, T.; Hughes, T.; White, D.
2013Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patientsRoss, D.; O'Hely, M.; Bartley, P.; Dang, P.; Score, J.; Goyne, J.; Sobrinho-Simoes, M.; Cross, N.; Melo, J.; Speed, T.; Hughes, T.; Morley, A.

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