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Issue Date
Title
Author(s)
2002
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
Branford, S.
;
Rudzki, Z.
;
Walsh, S.
;
Grigg, A.
;
Arthur, C.
;
Taylor, K.
;
Herrmann, R.
;
Lynch, K.
;
Hughes, T.
2003
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
Branford, S.
;
Rudzki, Z.
;
Walsh, S.
;
Parkinson, I.
;
Grigg, A.
;
Szer, J.
;
Taylor, K.
;
Hermann, R.
;
Seymour, J.
;
Arthur, C.
;
Joske, D.
;
Lynch, K.
;
Hughes, T.
Discover
Author
2
Arthur, C.
2
Branford, S.
2
Grigg, A.
2
Lynch, K.
2
Walsh, S.
1
Hermann, R.
1
Herrmann, R.
1
Joske, D.
1
Parkinson, I.
1
Seymour, J.
.
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Subject
2
Adenosine Triphosphate
2
Adult
2
Benzamides
2
Binding Sites
2
DNA Mutational Analysis
2
Drug Resistance, Neoplasm
2
Female
2
Humans
2
Imatinib Mesylate
2
Leukemia, Myelogenous, Chronic, B...
.
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Date issued
1
2003
1
2002