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https://hdl.handle.net/2440/5903
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Type: | Journal article |
Title: | An evaluation of the relative efficacy of an open airway, an oxygen reservoir and continuous positive airway pressure 5 cmH2O on the non-ventilated lung |
Author: | Slimani, J. Russell, W. Jurisevic, C. |
Citation: | Anaesthesia and Intensive Care, 2004; 32(6):756-760 |
Publisher: | Australian Soc Anaesthetists |
Issue Date: | 2004 |
ISSN: | 0310-057X 1448-0271 |
Statement of Responsibility: | J. Slimani, W. J. Russell, C. Jurisevic |
Abstract: | The aim of this study, during one-lung ventilation, was to evaluate if oxygenation could be improved by use of a simple oxygen reservoir or application of 5 cmH2O continuous positive airway pressure (CPAP) to the non-ventilated lung compared with an open airway. Twenty-three patients with lung malignancy, undergoing thoracotomy requiring at least 60 minutes of one-lung ventilation before lung lobe excision, were studied. After routine induction and establishment of one-lung ventilation, the three treatments were applied in turn to the same patient in a sequence selected randomly. The first treatment was repeated as a fourth treatment and these results of the repeated treatment averaged to minimize the effect of slow changes. Arterial oxygenation was measured by an arterial blood gas 15 minutes after the application of each treatment. Twenty patients completed the study. Mean PaO2 (in mmHg) was 210.3 (SD 105.5) in the 'OPEN' treatment, 186.0 (SD 109.2) in the 'RESERVOIR' treatment, and 240.5 (SD 116.0) in the 'CPAP' treatment. This overall difference was not quite significant (P=0.058, paired ANOVA), but comparison of the pairs showed that there was a significant better oxygenation only with the CPAP compared to the reservoir treatments (t=2.52, P=0.021). While the effect on the surgical field was not apparent in most patients, in one patient surgery was impeded during CPAP. Our results show that the use of a reservoir does not give oxygenation better than an open tube, and is less effective than the use of CPAP 5 cmH2O on the non-ventilated lung during one-lung ventilation. |
Keywords: | Humans Lung Neoplasms Carbon Dioxide Oxygen Blood Gas Analysis Oxygen Inhalation Therapy Positive-Pressure Respiration Intraoperative Period Pneumonectomy Thoracotomy Analysis of Variance Probability Sensitivity and Specificity Oxygen Consumption Respiratory Mechanics Female Male Evaluation Studies as Topic |
Description: | Publisher's copy made available with the permission of the publisher © Australian Society of Anaesthetists |
DOI: | 10.1177/0310057x0403200604 |
Description (link): | http://www.aaic.net.au/Article.asp?D=2004043 |
Published version: | http://dx.doi.org/10.1177/0310057x0403200604 |
Appears in Collections: | Anaesthesia and Intensive Care publications Aurora harvest |
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File | Description | Size | Format | |
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Slimani.pdf | 167.52 kB | Publisher's PDF | View/Open |
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