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Preview	Issue Date	Title	Author(s)
	2021	Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial	Shehabi, Y.; Serpa Neto, A.; Howe, B.D.; Bellomo, R.; Arabi, Y.M.; Bailey, M.; Bass, F.E.; Kadiman, S.B.; McArthur, C.J.; Reade, M.C.; Seppelt, I.M.; Takala, J.; Wise, M.P.; Webb, S.A.; Mashonganyika, C.; McKee, H.; Tonks, A.; Donnelly, A.; Hemmings, N.; O’Kane, S.; et al.
	2021	Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer	Singhal, D.; Hahn, C.N.; Feurstein, S.; Wee, L.Y.A.; Moma, L.; Kutyna, M.M.; Chhetri, R.; Eshraghi, L.; Schreiber, A.W.; Feng, J.; Wang, P.P.-S.; Babic, M.; Parker, W.T.; Gao, S.; Moore, S.; Das, S.; Thomas, D.; Pattnaik, S.; Brown, A.L.; D'Andrea, R.J.; et al.
	2021	Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group	Opel, N.; Thalamuthu, A.; Milaneschi, Y.; Grotegerd, D.; Flint, C.; Leenings, R.; Goltermann, J.; Richter, M.; Hahn, T.; Woditsch, G.; Berger, K.; Hermesdorf, M.; McIntosh, A.; Whalley, H.C.; Harris, M.A.; MacMaster, F.P.; Walter, H.; Veer, I.M.; Frodl, T.; Carballedo, A.; et al.
	2021	Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia	Ochi, Y.; Yoshida, K.; Huang, Y.-J.; Kuo, M.-C.; Nannya, Y.; Sasaki, K.; Mitani, K.; Hosoya, N.; Hiramoto, N.; Ishikawa, T.; Branford, S.; Shanmuganathan, N.; Ohyashiki, K.; Takahashi, N.; Takaku, T.; Tsuchiya, S.; Kanemura, N.; Nakamura, N.; Ueda, Y.; Yoshihara, S.; et al.
	2021	Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease.	Jiang, S.H.; Mercan, S.; Papa, I.; Moldovan, M.; Walters, G.D.; Koina, M.; Fadia, M.; Stanley, M.; Lea-Henry, T.; Cook, A.; Ellyard, J.; McMorran, B.; Sundaram, M.; Thomson, R.; Canete, P.F.; Hoy, W.; Hutton, H.; Srivastava, M.; McKeon, K.; de la Rúa Figueroa, I.; et al.
	2021	Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity	Cao, E.; Watt, M.J.; Nowell, C.J.; Quach, T.; Simpson, J.S.; De Melo Ferreira, V.; Agarwal, S.; Chu, H.; Srivastava, A.; Anderson, D.; Gracia, G.; Lam, A.; Segal, G.; Hong, J.; Hu, L.; Phang, K.L.; Escott, A.B.J.; Windsor, J.A.; Phillips, A.R.J.; Creek, D.J.; et al.
	2021	Transcriptional signature in microglia associated with Aβ plaque phagocytosis	Grubman, A.; Choo, X.Y.; Chew, G.; Ouyang, J.F.; Sun, G.; Croft, N.P.; Rossello, F.J.; Simmons, R.; Buckberry, S.; Landin, D.V.; Pflueger, J.; Vandekolk, T.H.; Abay, Z.; Zhou, Y.; Liu, X.; Chen, J.; Larcombe, M.; Haynes, J.M.; McLean, C.; Williams, S.; et al.
	2021	The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study	Hodgson, C.L.; Higgins, A.M.; Bailey, M.J.; Mather, A.M.; Beach, L.; Bellomo, R.; Bissett, B.; Boden, I.J.; Bradley, S.; Burrell, A.; Cooper, D.J.; Fulcher, B.J.; Haines, K.J.; Hopkins, J.; Jones, A.Y.M.; Lane, S.; Lawrence, D.; van der Lee, L.; Liacos, J.; Linke, N.J.; et al.
	2021	Co-designing health service evaluation tools that foreground first nation worldviews for better mental health and wellbeing outcomes	Wright, M.; Getta, A.D.; Green, A.O.; Kickett, U.C.; Kickett, A.H.; McNamara, A.I.; McNamara, U.A.; Newman, A.M.; Pell, A.C.; Penny, A.M.; Wilkes, U.P.; Wilkes, A.S.; Culbong, T.; Taylor, K.; Brown, A.; Dudgeon, P.; Pearson, G.; Allsop, S.; Lin, A.; Smith, G.; et al.
	2021	γδ T cells in merkel cell carcinomas have a proinflammatory profile prognostic of patient survival	Gherardin, N.A.; Waldeck, K.; Caneborg, A.; Martelotto, L.G.; Balachander, S.; Zethoven, M.; Petrone, P.M.; Pattison, A.; Wilmott, J.S.; Quiñones-Parra, S.M.; Rossello, F.; Posner, A.; Wong, A.; Weppler, A.M.; Shannon, K.F.; Hong, A.; Ferguson, P.M.; Jakrot, V.; Raleigh, J.; Hatzimihalis, A.; et al.