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PreviewIssue DateTitleAuthor(s)
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2018Tight junction protein claudin-2 promotes self-renewal of human colorectal cancer stem-like cellsPaquet-Fifield, S.; Koh, S.L.; Cheng, L.; Beyit, L.M.; Shembrey, C.; Mølck, C.; Behrenbruch, C.; Papin, M.; Gironella, M.; Guelfi, S.; Nasr, R.; Grillet, F.; Prudhomme, M.; Bourgaux, J.F.; Castells, A.; Pascussi, J.M.; Heriot, A.G.; Puisieux, A.; Davis, M.J.; Pannequin, J.; et al.
2013Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitorsWaibel, M.; Solomon, V.; Knight, D.; Ralli, R.; Kim, S.; Banks, K.; Vidacs, E.; Virely, C.; Sia, K.; Bracken, L.; Collins-Underwood, R.; Drenberg, C.; Ramsey, L.; Meyer, S.; Takiguchi, M.; Dickins, R.; Levine, R.; Ghysdael, J.; Dawson, M.; Lock, R.; et al.
2017Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell populationHein, N.; Cameron, D.; Hannan, K.; Nguyen, N.; Fong, C.; Sornkom, J.; Wall, M.; Pavy, M.; Cullinane, C.; Diesch, J.; Devlin, J.; George, A.; Sanij, E.; Quin, J.; Poortinga, G.; Verbrugge, I.; Baker, A.; Drygin, D.; Harrison, S.; Rozario, J.; et al.

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