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PreviewIssue DateTitleAuthor(s)
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2019Bcl-2 is a therapeutic target for hypodiploid b-lineage acute lymphoblastic leukemiaDiaz-Flores, E.; Comeaux, E.Q.; Kim, K.L.; Melnik, E.; Beckman, K.; Davis, K.L.; Wu, K.; Akutagawa, J.; Bridges, O.; Marino, R.; Wohlfeil, M.; Braun, B.S.; Mullighan, C.G.; Loh, M.L.
2019Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastomaNeubauer, H.A.; Tea, M.N.; Zebol, J.R.; Gliddon, B.L.; Stefanidis, C.; Moretti, P.A.B.; Pitman, M.R.; Costabile, M.; Kular, J.; Stringer, B.W.; Day, B.W.; Samuel, M.S.; Bonder, C.S.; Powell, J.A.; Pitson, S.M.
2019Thymus-derived regulatory T cells exhibit Foxp3 epigenetic modification and phenotype attenuation after mating in miceMoldenhauer, L.M.; Schjenken, J.E.; Hope, C.M.; Green, E.S.; Zhang, B.; Eldi, P.; Hayball, J.D.; Barry, S.C.; Robertson, S.A.
2019Alpha-Blockers as colorectal cancer chemopreventive: findings from a case-control study, human cell cultures, and in vivo preclinical testingSuzuki, N.; Niikura, R.; Ihara, S.; Hikiba, Y.; Kinoshita, H.; Higashishima, N.; Hayakawa, Y.; Yamada, A.; Hirata, Y.; Nakata, R.; Okamoto, M.; Sano, M.; Kushiyama, A.; Ichinose, M.; Woods, S.L.; Worthley, D.; Iwamoto, Y.; Koike, K.
2019TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory NetworkSeruggia, D.; Oti, M.; Tripathi, P.; Canver, M.C.; LeBlanc, L.; Di Giammartino, D.C.; Bullen, M.J.; Nefzger, C.M.; Sun, Y.B.Y.; Farouni, R.; Polo, J.M.; Pinello, L.; Apostolou, E.; Kim, J.; Orkin, S.H.; Das, P.P.
2019Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunkGrimm, L.; Nakajima, H.; Chaudhury, S.; Bower, N.I.; Okuda, K.S.; Cox, A.G.; Harvey, N.L.; Koltowska, K.; Mochizuki, N.; Hogan, B.M.