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PreviewIssue DateTitleAuthor(s)
2019APOMAB antibody-drug conjugates targeting dead tumor cells are effective in vivoStaudacher, A.H.; Li, Y.; Liapis, V.; Hou, J.J.C.; Chin, D.; Dolezal, O.; Adams, T.E.; van Berkel, P.H.; Brown, M.P.
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2019Bcl-2 is a therapeutic target for hypodiploid b-lineage acute lymphoblastic leukemiaDiaz-Flores, E.; Comeaux, E.Q.; Kim, K.L.; Melnik, E.; Beckman, K.; Davis, K.L.; Wu, K.; Akutagawa, J.; Bridges, O.; Marino, R.; Wohlfeil, M.; Braun, B.S.; Mullighan, C.G.; Loh, M.L.
2019International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine gliomaTsoli, M.; Shen, H.; Mayoh, C.; Franshaw, L.; Ehteda, A.; Upton, D.; Carvalho, D.; Vinci, M.; Meel, M.H.; van Vuurden, D.; Plessier, A.; Castel, D.; Drissi, R.; Farrell, M.; Cryan, J.; Crimmins, D.; Caird, J.; Pears, J.; Francis, S.; Ludlow, L.E.A.; et al.
2019Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastomaNeubauer, H.A.; Tea, M.N.; Zebol, J.R.; Gliddon, B.L.; Stefanidis, C.; Moretti, P.A.B.; Pitman, M.R.; Costabile, M.; Kular, J.; Stringer, B.W.; Day, B.W.; Samuel, M.S.; Bonder, C.S.; Powell, J.A.; Pitson, S.M.
2019Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemiaMoujalled, D.M.; Pomilio, G.; Ghiurau, C.; Ivey, A.; Salmon, J.; Rijal, S.; Macraild, S.; Zhang, L.; Teh, T.C.; Tiong, I.S.; Lan, P.; Chanrion, M.; Claperon, A.; Rocchetti, F.; Zichi, A.; Kraus-Berthier, L.; Wang, Y.; Halilovic, E.; Morris, E.; Colland, F.; et al.
2019Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemiaBell, C.C.; Fennell, K.A.; Chan, Y.C.; Rambow, F.; Yeung, M.M.; Vassiliadis, D.; Lara, L.; Yeh, P.; Martelotto, L.G.; Rogiers, A.; Kremer, B.E.; Barbash, O.; Mohammad, H.P.; Johanson, T.M.; Burr, M.L.; Dhar, A.; Karpinich, N.; Tian, L.; Tyler, D.S.; MacPherson, L.; et al.