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PreviewIssue DateTitleAuthor(s)
2021Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancerSinghal, D.; Hahn, C.N.; Feurstein, S.; Wee, L.Y.A.; Moma, L.; Kutyna, M.M.; Chhetri, R.; Eshraghi, L.; Schreiber, A.W.; Feng, J.; Wang, P.P.-S.; Babic, M.; Parker, W.T.; Gao, S.; Moore, S.; Das, S.; Thomas, D.; Pattnaik, S.; Brown, A.L.; D'Andrea, R.J.; et al.
2019ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variantsLuo, X.; Feurstein, S.; Mohan, S.; Porter, C.C.; Jackson, S.A.; Keel, S.; Chicka, M.; Brown, A.L.; Kesserwan, C.; Agarwal, A.; Luo, M.; Li, Z.; Ross, J.E.; Baliakas, P.; Pineda-Alvarez, D.; DiNardo, C.D.; Bertuch, A.A.; Mehta, N.; Vulliamy, T.; Wang, Y.; et al.
2020RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AMLBrown, A.L.; Arts, P.; Carmichael, C.L.; Babic, M.; Dobbins, J.; Chong, C.-E.; Schreiber, A.W.; Feng, J.; Phillips, K.; Wang, P.P.S.; Ha, T.; Homan, C.C.; King-Smith, S.L.; Rawlings, L.; Vakulin, C.; Dubowsky, A.; Burdett, J.; Moore, S.; McKavanagh, G.; Henry, D.; et al.
2016Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignanciesLewinsohn, M.; Brown, A.L.; Weinel, L.M.; Phung, C.; Rafidi, G.; Lee, M.K.; Schreiber, A.W.; Feng, J.; Babic, M.; Chong, C.E.; Lee, Y.; Yong, A.; Suthers, G.K.; Poplawski, N.; Altree, M.; Phillips, K.; Jaensch, L.; Fine, M.; D'Andrea, R.J.; Lewis, I.D.; et al.
2023TP53 mutation variant allele frequency of ≥10% is associated with poor prognosis in therapy-related myeloid neoplasmsShah, M.V.; Tran, E.N.H.; Shah, S.; Chhetri, R.; Baranwal, A.; Ladon, D.; Shultz, C.; Al-Kali, A.; Brown, A.L.; Chen, D.; Scott, H.S.; Greipp, P.; Thomas, D.; Alkhateeb, H.B.; Singhal, D.; Gangat, N.; Kumar, S.; Patnaik, M.M.; Hahn, C.N.; Kok, C.H.; et al.
2022Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.Lewis, A.C.; Pope, V.S.; Tea, M.N.; Li, M.; Nwosu, G.O.; Nguyen, T.M.; Wallington-Beddoe, C.T.; Moretti, P.A.; Anderson, D.; Creek, D.J.; Costabile, M.; Ali, S.R.; Thompson-Peach, C.A.; Dredge, B.K.; Bert, A.G.; Goodall, G.J.; Ekert, P.G.; Brown, A.L.; D'Andrea, R.J.; Robinson, N.; et al.
2022Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemiaBassal, M.A.; Samaraweera, S.E.; Lim, K.; Bernard, B.A.; Bailey, S.; Kaur, S.; Leo, P.; Toubia, J.; Thompson-Peach, C.; Nguyen, T.; Maung, K.Z.Y.; Casolari, D.A.; Iarossi, D.G.; Pagani, I.S.; Powell, J.; Pitson, S.; Natera, S.; Roessner, U.; Lewis, I.D.; Brown, A.L.; et al.
2016Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemiaLi, S.; Garrett-Bakelman, F.E.; Chung, S.S.; Sanders, M.A.; Hricik, T.; Rapaport, F.; Patel, J.; Dillon, R.; Vijay, P.; Brown, A.L.; Perl, A.E.; Cannon, J.; Bullinger, L.; Luger, S.; Becker, M.; Lewis, I.D.; To, L.B.; Delwel, R.; Löwenberg, B.; Döhner, H.; et al.

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