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https://hdl.handle.net/2440/61884
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Type: | Journal article |
Title: | Australasian Laparoscopic Colon Cancer Study shows that elderly patients may benefit from lower postoperative complication rates following laparoscopic versus open resection |
Author: | Allardyce, R. Bagshaw, P. Frampton, C. Frizelle, F. Hewett, P. Rieger, N. Smith, J. Solomon, M. Stevenson, A. |
Citation: | British Journal of Surgery, 2010; 97(1):86-91 |
Publisher: | John Wiley & Sons Ltd |
Issue Date: | 2010 |
ISSN: | 0007-1323 1365-2168 |
Statement of Responsibility: | R. A. Allardyce, P. F. Bagshaw, C. M. Frampton, F. A. Frizelle, P. J. Hewett, N. A. Rieger, J. S. Smith, M. J. Solomon and A. R. L. Stevenson for the Australasian Laparoscopic Colon Cancer Study Group |
Abstract: | <h4>Background</h4>A retrospective analysis of age-related postoperative morbidity in the Australia and New Zealand prospective randomized controlled trial comparing laparoscopic and open resection for right- and left-sided colonic cancer is presented.<h4>Methods</h4>A total of 592 eligible patients were entered and studied from 1998 to 2005.<h4>Results</h4>Data from 294 patients who underwent laparoscopic and 298 who had open colonic resection were analysed; 266 patients were aged less than 70 years and 326 were 70 years or older (mean(s.d.) 70.3(11.0) years). Forty-three laparoscopic operations (14.6 per cent) were converted to an open procedure. Fewer complications were reported for intention-to-treat laparoscopic resections compared with open procedures (P = 0.002), owing primarily to a lower rate in patients aged 70 years or more (P = 0.002). Fewer patients in the laparoscopic group experienced any complication (P = 0.035), especially patients aged 70 years or above (P = 0.019).<h4>Conclusion</h4>Treatment choices for colonic cancer depend principally upon disease-free survival; however, patients aged 70 years or over should have rigorous preoperative investigation to avoid conversion and should be considered for laparoscopic colonic resection.<h4>Registration number</h4>NCT00202111 (http://www.clinicaltrials.gov). |
Keywords: | Australasian Laparoscopic Colon Cancer Study Group Humans Colonic Neoplasms Postoperative Complications Laparoscopy Disease-Free Survival Length of Stay Retrospective Studies Prospective Studies Age Factors Quality of Life Aged Aged, 80 and over |
Rights: | Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. |
DOI: | 10.1002/bjs.6785 |
Published version: | http://dx.doi.org/10.1002/bjs.6785 |
Appears in Collections: | Aurora harvest 5 Surgery publications |
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