Adelaide Research & Scholarship
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https://hdl.handle.net/2440/65023
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| Type: | Journal article |
| Title: | Myc-modulated miR-9 makes more metastases |
| Author: | Khew-Goodall, Y. Goodall, G. |
| Citation: | Nature Cell Biology, 2010; 12(3):209-211 |
| Publisher: | Nature Publishing Group |
| Issue Date: | 2010 |
| ISSN: | 1465-7392 1476-4679 |
| Statement of Responsibility: | Yeesim Khew-Goodall and Gregory J. Goodall |
| Abstract: | The microRNA miR-9 is induced by Myc in breast cancer cells where it targets the major epithelial adherens junction protein, E-cadherin. This primes the cancer cells for epithelial-mesenchymal transition (EMT) and also stimulates angiogenesis in tumours. |
| Keywords: | Animals Humans Mice Neoplasms Neuroblastoma Breast Neoplasms Neoplasm Invasiveness Neoplasm Metastasis Neovascularization, Pathologic Vimentin Vascular Endothelial Growth Factor A Proto-Oncogene Proteins c-myc Cadherins Oncogene Proteins Nuclear Proteins MicroRNAs Antigens, CD Transplantation, Heterologous Signal Transduction Cell Proliferation Down-Regulation Gene Expression Regulation, Neoplastic Models, Biological Female beta Catenin Cell Transdifferentiation N-Myc Proto-Oncogene Protein |
| Rights: | © 2010 Macmillan Publishers Limited. All rights reserved. |
| DOI: | 10.1038/ncb0310-209 |
| Published version: | http://dx.doi.org/10.1038/ncb0310-209 |
| Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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