Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/66058
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | VEGF receptor signalling in vertebrate development |
Author: | Vieira, J. Ruhrberg, C. Schwarz, Q. |
Citation: | Organogenesis, 2010; 6(2):97-106 |
Publisher: | Landes Bioscience |
Issue Date: | 2010 |
ISSN: | 1547-6278 1555-8592 |
Statement of Responsibility: | Joaquim Miguel Vieira, Christiana Ruhrberg and Quenten Schwarz |
Abstract: | The secreted glycoprotein vascular endothelial growth factor A (VEGF or VEGFA) affects many different cell types and modifies a wide spectrum of cellular behaviors in tissue culture models, including proliferation, migration, differentiation and survival. The versatility of VEGF signaling is reflected in the complex composition of its cell surface receptors and their ability to activate a variety of different downstream signaling molecules. A major challenge for VEGF research is to determine which of the specific signaling pathways identified in vitro control development and homeostasis of tissues containing VEGF-responsive cell types in vivo. |
Keywords: | VEGF VEGFR1 VEGFR2 FLT1 KDR FLK1 neuropilin HSPG |
Rights: | Copyright © 2010 Landes Bioscience |
DOI: | 10.4161/org.6.2.11686 |
Description (link): | http://www.mendeley.com/research/vegf-receptor-signalling-in-vertebrate-development/ |
Published version: | http://dx.doi.org/10.4161/org.6.2.11686 |
Appears in Collections: | Aurora harvest 5 Molecular and Biomedical Science publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.