Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/7182
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wiltshire, E. | - |
dc.contributor.author | Hirte, C. | - |
dc.contributor.author | Couper, J. | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Diabetes Care, 2003; 26(5):1356-1361 | - |
dc.identifier.issn | 0149-5992 | - |
dc.identifier.issn | 1935-5548 | - |
dc.identifier.uri | http://hdl.handle.net/2440/7182 | - |
dc.description | Copyright © 2003 by the American Diabetes Association. | - |
dc.description.abstract | <h4>Objective</h4>To determine the relative influence of diet, metabolic control, and familial factors on lipids in children with type 1 diabetes and control subjects.<h4>Research design and methods</h4>We assessed fasting serum cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, lipoprotein(a), apolipoprotein (apo)-A1, and apoB in 79 children and adolescents with type 1 diabetes and 61 age- and sex-matched control subjects, together with dietary intakes using a quantitative food frequency questionnaire.<h4>Results</h4>Total cholesterol, LDL cholesterol, apoB, HDL cholesterol, and apoA1 were significantly higher in children with diabetes. Children with diabetes had higher percentage energy intake from complex carbohydrates (P = 0.001) and fiber intake (P = 0.02), and they had lower intake of refined sugar (P < 0.001) and percentage energy from saturated fat (P = 0.045) than control subjects. Total cholesterol (beta = 0.43, P < 0.001), LDL cholesterol (beta = 0.4, P < 0.001), and apoB (beta = 0.32, P = 0.006) correlated independently with HbA(1c) but not dietary intake. HDL cholesterol (beta = 0.24, P = 0.05) and apoA1 (beta = 0.32, P = 0.004) correlated independently with HbA(1c), and HDL cholesterol (beta = -0.34, P = 0.009) correlated with percentage energy intake from complex carbohydrates. Triglycerides correlated independently with percentage energy intake from complex carbohydrates (beta = 0.33, P = 0.01) and insulin dose (beta = 0.26, P = 0.04). Subjects with diabetes and elevated LDL (>3.35 mmol/l, >130 mg/dl), for whom dietary therapy would be recommended, had significantly higher HbA(1c) (P = 0.007), but they had higher intake of complex carbohydrates than subjects with LDL cholesterol <3.35 mmol/l.<h4>Conclusions</h4>Lipid abnormalities remain common in children and adolescents with type 1 diabetes who adhere to current dietary recommendations, and they relate to metabolic control but not dietary intake. | - |
dc.description.statementofresponsibility | Esko J. Wiltshire, Craig Hirte and Jennifer J. Couper | - |
dc.language.iso | en | - |
dc.publisher | Amer Diabetes Assoc | - |
dc.source.uri | http://dx.doi.org/10.2337/diacare.26.5.1356 | - |
dc.subject | Humans | - |
dc.subject | Diabetes Mellitus, Type 1 | - |
dc.subject | Cholesterol | - |
dc.subject | Insulin | - |
dc.subject | Dietary Fats | - |
dc.subject | Triglycerides | - |
dc.subject | Lipoproteins | - |
dc.subject | Lipoprotein(a) | - |
dc.subject | Feeding Behavior | - |
dc.subject | Adolescent | - |
dc.subject | Child | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Hyperlipidemias | - |
dc.subject | Surveys and Questionnaires | - |
dc.subject | Glycated Hemoglobin | - |
dc.title | Dietary fats do not contribute to hyperlipidemia in children and adolescents with type 1 diabetes | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.2337/diacare.26.5.1356 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Couper, J. [0000-0003-4448-8629] | - |
Appears in Collections: | Aurora harvest 5 Paediatrics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.