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https://hdl.handle.net/2440/71957
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DC Field | Value | Language |
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dc.contributor.author | Simon, S. | - |
dc.contributor.author | Torpy, D. | - |
dc.contributor.author | Brophy, B. | - |
dc.contributor.author | Blumbergs, P. | - |
dc.contributor.author | Selva-Nayagam, D. | - |
dc.contributor.author | Crompton, J. | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | New Zealand Medical Journal, 2011; 124(1335):52-59 | - |
dc.identifier.issn | 1175-8716 | - |
dc.identifier.issn | 1175-8716 | - |
dc.identifier.uri | http://hdl.handle.net/2440/71957 | - |
dc.description.abstract | Objective: To report the neuro-ophthalmic manifestations and outcomes in patients with pituitary apoplexy. Method Retrospective chart review. Results: 23 patients were identified (17 men, mean age 54.1 years (range 23–86 years). The onset was abrupt in 22 patients; one patient had a subclinical presentation. Headache was the commonest presenting symptom (82.6%, 19/23). Neuro-ophthalmic manifestations were present in more than three-quarters of the patients (82.6%, 19/23). At presentation, 55 % (11/20), 47.6 % (10/21) and 60.9 % (14/23) of the patients had reduced visual acuity, field defects and cranial nerve palsies respectively. Management was conservative in 4 patients and surgical in 18 patients; one patient died shortly after presentation. The median follow up period was 10.5 months (22 patients, range 0.2–168 months). At final follow up, improvement was present in 100% of the patients with reduced acuity (8/8) and ocular palsy (13/13) and 81.8% of patients with field deficits (9/11). Age, sex, presence of precipitating factors and timing of surgery did not have an impact on neuro-ophthalmic recovery. Conclusion: Pituitary apoplexy should be considered in any patient with abrupt onset of neuro-ophthalmic deficits. Prompt medical and surgical management is lifesaving and can lead to significant improvement in visual and cranial nerve deficits. | - |
dc.description.statementofresponsibility | Sumu Simon, David Torpy, Brian Brophy, Peter Blumbergs, Dinesh Selva, John L Crompton | - |
dc.language.iso | en | - |
dc.publisher | Southern Colour Print | - |
dc.rights | © NZMA | - |
dc.source.uri | http://www.nzma.org.nz/journal/124-1335/4685/ | - |
dc.subject | Humans | - |
dc.subject | Prolactinoma | - |
dc.subject | Adenoma | - |
dc.subject | Pituitary Neoplasms | - |
dc.subject | Brain Ischemia | - |
dc.subject | Cerebral Infarction | - |
dc.subject | Cerebral Hemorrhage | - |
dc.subject | Pituitary Apoplexy | - |
dc.subject | Hypopituitarism | - |
dc.subject | Cranial Nerve Diseases | - |
dc.subject | Headache | - |
dc.subject | Vision Disorders | - |
dc.subject | Diplopia | - |
dc.subject | Nausea | - |
dc.subject | Vomiting | - |
dc.subject | Diagnostic Errors | - |
dc.subject | Retrospective Studies | - |
dc.subject | Follow-Up Studies | - |
dc.subject | Visual Acuity | - |
dc.subject | Visual Fields | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Aged, 80 and over | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Young Adult | - |
dc.title | Neuro-ophthalmic manifestations and outcomes of pituitary apoplexy - a life and sight-threatening emergency | - |
dc.type | Journal article | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Torpy, D. [0000-0002-5069-0981] | - |
dc.identifier.orcid | Selva-Nayagam, D. [0000-0002-2169-5417] | - |
Appears in Collections: | Aurora harvest 5 Opthalmology & Visual Sciences publications |
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