Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/7459
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Partial seizures with focal epileptogenic electroencephalographic patterns in three related female patients with fragile-X syndrome |
Author: | Singh, R. Sutherland, G. Manson, J. |
Citation: | Journal of Child Neurology, 1999; 14(2):108-112 |
Publisher: | DECKER PERIODICALS INC |
Issue Date: | 1999 |
ISSN: | 1708-8283 1708-8283 |
Statement of Responsibility: | Rita Singh, Grant R. Sutherland, and James Manson |
Abstract: | Epilepsy and abnormal electroencephalographic (EEG) patterns have been reported in mentally retarded males with fragile-X syndrome, but the high incidence of epilepsy in such persons has been recognized only recently. These individuals have focal spikes in the EEG similar to the benign rolandic pattern. Female carriers have very rarely been reported to have epilepsy or nonspecific abnormal EEG patterns. We report partial seizures with a focal epileptogenic EEG pattern in two sisters and their grandmother, who are all carriers of fragile-X syndrome. The sisters have mild developmental delay, but the grandmother is of normal intelligence. The mother of the two sisters is known to be a carrier of the fragile-X chromosome and is of normal intelligence, with no history of seizures. It is important for physicians to be aware of the possibility that females presenting with partial seizures of unknown cause may be fragile-X carriers, and enquiry for a family history of intellectual disability should be pursued. |
Keywords: | Humans Epilepsies, Partial Fragile X Syndrome Electroencephalography Pedigree Intelligence Adult Child Child, Preschool Female |
Rights: | Copyright status unknown |
DOI: | 10.1177/088307389901400208 |
Published version: | http://dx.doi.org/10.1177/088307389901400208 |
Appears in Collections: | Aurora harvest 5 Paediatrics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.