Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/74884
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DC Field | Value | Language |
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dc.contributor.author | Warren-Smith, S. | - |
dc.contributor.author | Nie, G. | - |
dc.contributor.author | Schartner, E. | - |
dc.contributor.author | Salamonsen, L. | - |
dc.contributor.author | Monro, T. | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Biomedical Optics Express, 2012; 3(12):1-10 | - |
dc.identifier.issn | 2156-7085 | - |
dc.identifier.issn | 2156-7085 | - |
dc.identifier.uri | http://hdl.handle.net/2440/74884 | - |
dc.description.abstract | A fluorescence-based enzyme activity assay has been demonstrated within a small-core microstructured optical fiber (MOF) for the first time. To achieve this, a reflection-based automated alignment system has been developed, which uses feedback and piezoelectric actuators to maintain optical alignment. The auto-alignment system provides optical stability for the time required to perform an activity assay. The chosen assay is based on the enzyme proprotein convertase 5/6 (PC6) and has important applications in women's health. | - |
dc.description.statementofresponsibility | Stephen C. Warren-Smith, Guiying Nie, Erik P. Schartner, Lois A. Salamonsen, and Tanya M. Monro | - |
dc.language.iso | en | - |
dc.publisher | Optical Society of America | - |
dc.rights | © 2012 OSA | - |
dc.source.uri | http://dx.doi.org/10.1364/boe.3.003304 | - |
dc.subject | (060.2370) Fiber optics sensors | - |
dc.subject | (060.4005) Microstructured fibers | - |
dc.subject | (280.1415) Biological sensing and sensors | - |
dc.title | Enzyme activity assays within microstructured optical fibers enabled by automated alignment | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1364/BOE.3.003304 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Warren-Smith, S. [0000-0002-2612-6344] | - |
dc.identifier.orcid | Schartner, E. [0000-0003-1669-4302] | - |
Appears in Collections: | Aurora harvest IPAS publications |
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