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https://hdl.handle.net/2440/75324
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Type: | Journal article |
Title: | Brain weight-body weight ratio in sudden infant death syndrome revisited |
Author: | Elliott, J. Vink, R. Jensen, L. Byard, R. |
Citation: | Medicine Science and the Law, 2012; 52(4):207-209 |
Publisher: | Chiltern Publishing |
Issue Date: | 2012 |
ISSN: | 0025-8024 2042-1818 |
Statement of Responsibility: | Jane A Elliott, Robert Vink, Lisbeth Jensen and Roger W Byard |
Abstract: | <h4>Aims</h4>To determine whether the brain-body weight ratio is increased in sudden infant death syndrome (SIDS).<h4>Methods</h4>Review of autopsy files from Forensic Science SA, South Australia was undertaken over an eight-year period from 1999 to 2006, with classification of cases according to the San Diego definition. Sudden and/or unexpected deaths in previously healthy infants due to asphyxia or infection were selected as controls.<h4>Results</h4>There were 42 SIDS cases and 25 controls. The SIDS cases were aged from 1 to 42 weeks (mean: 16.26 ± 1.5 weeks) with a male to female ratio of 26:16. The control infants were aged from 3 to 48 weeks (mean: 19.24 ± 2.9 weeks) (P > 0.05) (M:F = 16:9) and included 13 cases of asphyxia and 12 cases of sepsis. Comparison of the brain-body weight ratios failed to demonstrate a significant difference: SIDS mean = 0.121 ± 0.003; control mean = 0.115 ± 0.003 (P > 0.05).<h4>Conclusion</h4>Although, there was a trend towards higher brain-body weight ratios in SIDS infants, this did not reach significance. The role of brain weight in the aetiology of SIDS remains controversial. |
Keywords: | Brain Humans Sudden Infant Death Body Weight Organ Size Case-Control Studies Forensic Pathology Infant Infant, Newborn Female Male |
Rights: | © British Academy of Forensic Sciences |
DOI: | 10.1258/msl.2012.011136 |
Published version: | http://dx.doi.org/10.1258/msl.2012.011136 |
Appears in Collections: | Aurora harvest Pathology publications |
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