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https://hdl.handle.net/2440/7621
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Type: | Journal article |
Title: | Paradoxical impact of body positioning on gastroesophageal reflux and gastric emptying in the premature neonate |
Author: | Omari, T. Rommel, N. Staunton, E. Lontis, R. Goodchild, L. Haslam, R. Dent, J. Davidson, G. |
Citation: | Journal of Pediatrics, 2004; 145(2):194-200 |
Publisher: | Mosby Inc |
Issue Date: | 2004 |
ISSN: | 0022-3476 1097-6833 |
Abstract: | <h4>Objectives</h4>To combine manometry and impedance to characterize the mechanisms of gastroesophageal reflux (GER) and to explore their relation to the rate of gastric emptying (GE) and body position.<h4>Study design</h4>Ten healthy preterm infants (35 to 37 weeks' postmenstrual age) were studied with the use of a micromanometric/impedance assembly. Episodes of GER were identified by impedance, and the mechanism(s) of GER triggering and GER clearance were characterized. GE was determined with a C13Na-octanoate breath test.<h4>Results</h4>Gastroesophageal reflux episodes (n=89) were recorded, consisting of 74% liquid, 14% gas, and 12% mixed. Transient lower esophageal sphincter relaxation (TLESR) was the predominant mechanism of reflux, triggering 83% of GER. Of 92 TLESRs recorded, 27% were not associated with reflux. Infants studied in the right lateral position had significantly (P <.01) more GER, a higher proportion of liquid GER (P <.05), and faster GE (P <.005) when compared with infants studied in the left lateral position.<h4>Conclusions</h4>In healthy preterm infants, GER is predominantly liquid in nature. Right-side positioning is associated with increased triggering of TLESR and GER despite accelerating GE. |
Keywords: | Humans Gastroesophageal Reflux Infant, Premature, Diseases Manometry Electric Impedance Gastric Emptying Posture Time Factors Infant, Newborn Female Male |
DOI: | 10.1016/j.jpeds.2004.05.026 |
Published version: | http://dx.doi.org/10.1016/j.jpeds.2004.05.026 |
Appears in Collections: | Aurora harvest Paediatrics publications |
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