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https://hdl.handle.net/2440/7891
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Type: | Journal article |
Title: | Autoaugmentation gastrocystoplasty and demucosalized gastrocystoplasty in a sheep model |
Author: | Dewan, P. Stefanek, W. Lorenz, C. Owen, A. Byard, R. |
Citation: | Urology, 1995; 45(2):291-295 |
Publisher: | Elsevier Science |
Issue Date: | 1995 |
ISSN: | 0090-4295 1527-9995 |
Statement of Responsibility: | P.A. Dewan, W. Stefanek, C. Lorenz, A.J. Owen, R.W. Byard |
Abstract: | <h4>Objectives</h4>To compare the normal sheep bladder at 6 and 12 months with bladders subjected to either an autoaugmentation gastrocystoplasty or a clam demucosalized gastrocystoplasty.<h4>Methods</h4>Twenty male lambs aged between 8 and 10 weeks had an autoaugmentation gastrocystoplasty in which de-epithelialized stomach muscle was added to an intact urothelium. The functional, radiologic, and histologic outcomes were compared with 11 animals who underwent a clam demucosalized gastrocystoplasty and 14 control animals. A total of 18 operated animals had a urodynamic study at 6 months and 9 at 12 months.<h4>Results</h4>The average bladder volume for the autoaugmentation gastrocystoplasty group at 12 months was greater than that of the control group (401 +/- 120 mL versus 205 +/- 77 mL). The demucosalized clam bladders had been less effectively enlarged (286 +/- 77 mL). The compliance values for autoaugmentation gastrocystoplasty animals were 14.7 +/- 11.3 mL/cm water (H2O) compared with 9.0 +/- 4.8 mL/cm H2O in the demucosalized gastrocystoplasty group, and 9.1 +/- 3.7 mL/cm H2O for the control animals.<h4>Conclusions</h4>The addition of the autoaugmentation procedure improves the prospect of enlarging the normal sheep bladder when using demucosalized gastric muscle. |
Keywords: | Stomach Gastric Mucosa Animals Sheep Radiography Male Urinary Bladder |
DOI: | 10.1016/0090-4295(95)80020-4 |
Published version: | http://dx.doi.org/10.1016/0090-4295(95)80020-4 |
Appears in Collections: | Aurora harvest 4 Paediatrics publications |
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