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https://hdl.handle.net/2440/79914
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Type: | Journal article |
Title: | Estimating renal function in morbidly obese patients |
Author: | Lovell, A. Game, P. Wittert, G. Thompson, C. |
Citation: | Obesity Surgery, 2013; 23(9):1427-1430 |
Publisher: | F D-Communications Inc |
Issue Date: | 2013 |
ISSN: | 0960-8923 1708-0428 |
Statement of Responsibility: | Alex Lovell, Philip Game, Gary Wittert, Campbell Thompson |
Abstract: | <h4>Background</h4>This paper aims to evaluate, in a clinical context, current creatinine-based formulas commonly used to calculate renal function in morbidly obese patients.<h4>Methods</h4>A retrospective analysis was performed of the estimates of renal function of 63 obese or morbidly obese patients undergoing gastric bypass surgery. Each patient's glomerular filtration rate (GFR) was calculated using five methods, both before and after surgery, and these approximations were then compared.<h4>Results</h4>Prior to surgery, the values offered by the five formulas for the renal function of this population ranged widely, by over a factor of 2. After surgery, the three weight-based GFR estimation methods indicated that a significant change in GFR had occurred, but the two non-weight-based formulas showed no significant change in estimated GFR.<h4>Conclusions</h4>At baseline and after significant weight loss, creatinine-based formulas differ twofold in their estimates of renal function of the morbidly obese. An accurate method for calculating these patients' renal function is required to improve patient safety with drug dosing as well as to ensure early detection of renal failure. |
Keywords: | GFR MDRD Weight loss Surgery |
Rights: | © Springer Science+Business Media New York 2013 |
DOI: | 10.1007/s11695-013-0890-6 |
Published version: | http://dx.doi.org/10.1007/s11695-013-0890-6 |
Appears in Collections: | Aurora harvest Surgery publications |
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