Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/80359
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Type: | Journal article |
Title: | A heterozygous moth genome provides insights into herbivory and detoxification |
Author: | You, M. Baxter, S. |
Citation: | Nature Genetics, 2013; 45(2):220-225 |
Publisher: | Nature Publishing Group |
Issue Date: | 2013 |
ISSN: | 1061-4036 1546-1718 |
Statement of Responsibility: | Minsheng You … Simon W Baxter … et al. |
Abstract: | How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemically related host plants1, but the genetic and molecular bases for adaptation to plant defense compounds remain poorly understood2. We report the first whole-genome sequence of a basal lepidopteran species, Plutella xylostella, which contains 18,071 protein-coding and 1,412 unique genes with an expansion of gene families associated with perception and the detoxification of plant defense compounds. A recent expansion of retrotransposons near detoxification-related genes and a wider system used in the metabolism of plant defense compounds are shown to also be involved in the development of insecticide resistance. This work shows the genetic and molecular bases for the evolutionary success of this worldwide herbivore and offers wider insights into insect adaptation to plant feeding, as well as opening avenues for more sustainable pest management. |
Keywords: | Chromosomes, Artificial, Bacterial Animals Moths Sulfatases Glucosinolates Gene Expression Profiling Sequence Analysis, DNA Computational Biology Pest Control Adaptation, Biological Evolution, Molecular Phylogeny Base Sequence Heterozygote Mutation Polymorphism, Single Nucleotide Genome Expressed Sequence Tags Molecular Sequence Data China Female Male Genetic Variation Molecular Sequence Annotation Real-Time Polymerase Chain Reaction Herbivory |
Rights: | This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
DOI: | 10.1038/ng.2524 |
Published version: | http://dx.doi.org/10.1038/ng.2524 |
Appears in Collections: | Aurora harvest 4 Molecular and Biomedical Science publications |
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hdl_80359.pdf | Published version | 1.84 MB | Adobe PDF | View/Open |
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