Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/81342
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Iridium(III) complexes containing 1,10-phenanthroline and derivatives: Synthetic, stereochemical, and structural studies, and their antimicrobial activity |
Author: | Pandrala, M. Li, F. Wallace, L. Steel, P. Moore, B. Autschbach, J. Collins, J. Keene, F. |
Citation: | Australian Journal of Chemistry: an international journal for chemical science, 2013; 66(9):1065-1073 |
Publisher: | C S I R O Publishing |
Issue Date: | 2013 |
ISSN: | 0004-9425 1445-0038 |
Statement of Responsibility: | Mallesh Pandrala, Fangfei Li, Lynne Wallace, Peter J. Steel, Barry Moore II, Jochen Autschbach, J. Grant Collins, and F. Richard Keene |
Abstract: | <jats:p> A convenient synthetic strategy is reported for the series of complexes [Ir(pp)3]3+ (where pp = phen, Me2phen and Me4phen) through the intermediacy of the appropriate [Ir(pp)2(CF3SO3)2]+ species. In the case of [Ir(phen)3]3+, the cation was resolved into its enantiomeric forms, for which the absolute configurations were determined by X-ray diffraction. The availability for the first time of the CD spectra allowed comparison with computed CD spectra. Measurement of the antimicrobial activity of the [Ir(pp)3]3+ species {and the [Ir(pp)2X2]+ (X = Cl–, CF3SO3–) precursors involved in their synthesis}, as well as cell uptake studies with the four bacterial strains S. aureus, methicillin-resistant S. aureus (MRSA), E. coli, and P. aeruginosa, indicated that they showed little activity compared with their Ru(ii) analogues. The results suggest that it is unfavourable for an individual metal centre with a 3+ charge to pass across the bacterial cell membrane. </jats:p> |
Rights: | Copyright status unknown |
DOI: | 10.1071/CH13264 |
Grant ID: | ARC |
Published version: | http://dx.doi.org/10.1071/ch13264 |
Appears in Collections: | Aurora harvest Chemistry and Physics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.