Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/82043
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Type: | Journal article |
Title: | Improving therapeutic ratio In head and neck cancer with adjuvant and cisplatin-based treatments |
Author: | Marcu, L. |
Citation: | BioMed Research International, 2013; 2013:1-9 |
Publisher: | Hindawi Publishing Corporation |
Issue Date: | 2013 |
ISSN: | 2314-6133 2314-6141 |
Statement of Responsibility: | Loredana G. Marcu |
Abstract: | Advanced head and neck cancers are difficult to manage despite the large treatment arsenal currently available. The multidisciplinary effort to increase disease-free survival and diminish normal tissue toxicity was rewarded with better locoregional control and sometimes fewer side effects. Nevertheless, locoregional recurrence is still one of the main reasons for treatment failure. Today, the standard of care in head and neck cancer management is represented by altered fractionation radiotherapy combined with platinum-based chemotherapy. Targeted therapies as well as chronotherapy were trialled with more or less success. The aim of the current work is to review the available techniques, which could contribute towards a higher therapeutic ratio in the treatment of advanced head and neck cancer patients. |
Keywords: | Humans Head and Neck Neoplasms Cisplatin Disease-Free Survival Chronotherapy Combined Modality Therapy Chemotherapy, Adjuvant |
Rights: | Copyright © 2013 Loredana G. Marcu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
DOI: | 10.1155/2013/817279 |
Published version: | http://dx.doi.org/10.1155/2013/817279 |
Appears in Collections: | Aurora harvest Chemistry and Physics publications |
Files in This Item:
File | Description | Size | Format | |
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hdl_82043.pdf | Published version | 1.33 MB | Adobe PDF | View/Open |
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