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https://hdl.handle.net/2440/83509
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Type: | Journal article |
Title: | Dynamic balancing: Deptor tips the scales |
Author: | Proud, C. |
Citation: | Journal of Molecular Cell Biology, 2009; 1(2):61-63 |
Publisher: | Oxford University Press |
Issue Date: | 2009 |
ISSN: | 1674-2788 1759-4685 |
Statement of Responsibility: | Christopher G. Proud |
Abstract: | The mammalian target of rapamycin, mTOR, is a key node in cellular regulation: its dysregulation is important in a number of disease states, including various cancers. A recent study identifies a new partner and regulator of mTOR, which can alter the balance of signaling downstream of mTOR and appears to be important in certain cancers, such as multiple myelomas. |
Keywords: | Animals Humans Multiple Myeloma Intracellular Signaling Peptides and Proteins Carrier Proteins Signal Transduction Enzyme Activation Protein Binding Models, Biological Proto-Oncogene Proteins c-akt TOR Serine-Threonine Kinases Protein Serine-Threonine Kinases |
Rights: | © The Author (2009). |
DOI: | 10.1093/jmcb/mjp012 |
Published version: | http://dx.doi.org/10.1093/jmcb/mjp012 |
Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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