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https://hdl.handle.net/2440/84421
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DC Field | Value | Language |
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dc.contributor.author | Burton, P. | - |
dc.contributor.author | Fortier, I. | - |
dc.contributor.author | Deschenes, M. | - |
dc.contributor.author | Hansell, A. | - |
dc.contributor.author | Palmer, L. | - |
dc.contributor.editor | Palmer, L. | - |
dc.contributor.editor | Smith, G. | - |
dc.contributor.editor | Burton, P. | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | An Introduction to Genetic Epidemiology, 2011 / Palmer, L., Smith, G., Burton, P. (ed./s), pp.155-174 | - |
dc.identifier.isbn | 9781861348975 | - |
dc.identifier.uri | http://hdl.handle.net/2440/84421 | - |
dc.description.abstract | Over the past decade and a half, genetic epidemiology has experienced an important shift from family-based studies of genetic linkage to individual-based studies of genetic association (Chapters One-Four). In part, this follows the recognition that if the 'common disease, common variant hypothesis'1-5 is true for at least a proportion of important genetic determinants of complex disease, these determinants - which will predominantly exhibit weak aetiological effects6 - will be identified more easily using association studies of population-based samples7. The shift to using association studies has been accompanied by an increasing methodological focus on optimal approaches to the design, analysis, meta-analysis and reporting of genetic association studies8-15; 65-67 (www.cdc.gov/genomics/ hugenet/strega.htm). This chapter describes these changes, and the growing international focus on biobanks with which they are associated. | - |
dc.description.statementofresponsibility | Paul R. Burton, Isabel Fortier, Mylene DeschĂȘnes, Anna Hansell, Lyle J. Palmer | - |
dc.language.iso | en | - |
dc.publisher | The Policy Press | - |
dc.title | Biobanks and biobank harmonisation | - |
dc.type | Book chapter | - |
dc.publisher.place | Bristol, UK | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Palmer, L. [0000-0002-1628-3055] | - |
Appears in Collections: | Aurora harvest Translational Health Science publications |
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