Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/8572
Type: Journal article
Title: Effect of posture on gastric emptying of nonnutrient liquids and antropyloroduodenal motility
Author: Anvari, M.
Horowitz, M.
Fraser, R.
Maddox, A.
Myers, J.
Dent, J.
Jamieson, G.
Citation: American Journal of Physiology. Gastrointestinal and Liver Physiology, 1995; 268(5):G868-G871
Publisher: American Physiological Society
Issue Date: 1995
ISSN: 0002-9513
Statement of
Responsibility: 
Anvari, Mehran, Michael Horowitz, Robert Fraser, Anne Maddox, Jennifer Myers, John Dent, and Glyn G. Jamieson.
Abstract: The effects of posture on gastric emptying, intragastric distribution, and antropyloroduodenal motility after ingestion of a nonnutrient liquid have been evaluated. In seven healthy volunteers antropyloroduodenal pressures were measured for 30 min after ingestion of 150 ml of normal saline in two different positions: sitting and left lateral. Saline drinks were radiolabeled and ingested both before and after intravenous atropine (4 micrograms/kg). Rates of emptying from both the total (P < 0.05) and the proximal (P < 0.05) stomach were faster in the sitting position than in the left lateral position. There were more long (> 6 cm) antropyloric pressure waves (P < 0.05) and isolated pyloric pressure waves (P < 0.05) in the sitting position. Intravenous atropine slowed emptying in both positions (P < 0.05) and in the sitting position decreased (P < 0.05) the number of antropyloric pressure waves. After atropine, gastric emptying was also faster in the sitting compared with the decubitus position (P < 0.05), although there was no difference in antropyloric or isolated pyloric pressure waves between the two postures. We conclude that the effects of gravity on gastric emptying of nonnutrient liquids are likely to reflect changes in both antropyloric motility and intragastric distribution.
Keywords: Duodenum; Pyloric Antrum; Pylorus; Humans; Sodium Chloride; Atropine; Drinking; Gastrointestinal Motility; Gastric Emptying; Posture; Adolescent; Adult; Female; Male
Rights: Copyright © 1995 the American Physiological Society
RMID: 0030005136
Published version: http://ajpgi.physiology.org/content/268/5/G868
Appears in Collections:Medicine publications

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