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Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/87807
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dc.contributor.authorMockenhaupt, F.P.-
dc.contributor.authorBedu-Addo, G.-
dc.contributor.authorJunge, C.-
dc.contributor.authorHommerich, L.-
dc.contributor.authorEggelte, T.A.-
dc.contributor.authorBienzle, U.-
dc.date.issued2007-
dc.identifier.citationAntimicrobial Agents and Chemotherapy, 2007; 51(1):332-334-
dc.identifier.issn0066-4804-
dc.identifier.issn1098-6596-
dc.identifier.urihttp://hdl.handle.net/2440/87807-
dc.description.abstractPlacental sequestration of Plasmodium falciparum in pregnancy may impair the usefulness of molecular markers of sulfadoxine-pyrimethamine resistance. In 300 infected, delivering women, the concordance of PCR-restriction fragment length polymorphism-derived parasite resistance alleles in matched samples from placenta and circulation was 83 to 98%. Sulfadoxine-pyrimethamine resistance typing in peripheral blood is reasonably representative of P. falciparum infecting pregnant women.-
dc.description.statementofresponsibilityFrank P. Mockenhaupt, George Bedu-Addo, Claudia Junge, Lena Hommerich, Teunis A. Eggelte, and Ulrich Bienzle-
dc.language.isoen-
dc.publisherAmerican Society for Microbiology-
dc.rightsCopyright © 2007, American Society for Microbiology-
dc.source.urihttp://dx.doi.org/10.1128/aac.00856-06-
dc.subjectPlacenta-
dc.subjectAnimals-
dc.subjectHumans-
dc.subjectPlasmodium falciparum-
dc.subjectPregnancy Complications, Parasitic-
dc.subjectMalaria, Falciparum-
dc.subjectSulfadoxine-
dc.subjectPyrimethamine-
dc.subjectTetrahydrofolate Dehydrogenase-
dc.subjectDrug Combinations-
dc.subjectAntimalarials-
dc.subjectPolymerase Chain Reaction-
dc.subjectPregnancy-
dc.subjectDrug Resistance-
dc.subjectGenotype-
dc.subjectMutation-
dc.subjectPolymorphism, Restriction Fragment Length-
dc.subjectAdolescent-
dc.subjectAdult-
dc.subjectMiddle Aged-
dc.subjectFemale-
dc.subjectBiomarkers-
dc.titleMarkers of sulfadoxine-pyrimethamine-resistant Plasmodium falciparum in placenta and circulation of pregnant women-
dc.typeJournal article-
dc.identifier.doi10.1128/AAC.00856-06-
pubs.publication-statusPublished-
Appears in Collections:Aurora harvest 2
Ecology, Evolution and Landscape Science publications

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