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https://hdl.handle.net/2440/89542
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Type: | Journal article |
Title: | Vitamin D in preterm infants: a prospective observational study |
Author: | Pinto, K. Collins, C. Gibson, R. Andersen, C. |
Citation: | Journal of Paediatrics and Child Health, 2015; 51(7):679-681 |
Publisher: | Wiley |
Issue Date: | 2015 |
ISSN: | 1034-4810 1440-1754 |
Statement of Responsibility: | Kieran Pinto, Carmel T Collins, Robert A Gibson, and Chad C Andersen |
Abstract: | AIM: Preterm infants are at increased risk of vitamin D deficiency as a result of both maternal deficiency and inadequate supplementation. The quantity and effectiveness of vitamin D supplementation in preterm infants are unclear. The aim of this study was to evaluate the natural history of vitamin D status in preterm infants and the effectiveness of the hospital's nutritional practices in meeting current supplementation recommendations. METHODS: A prospective observational study was undertaken in the Neonatal Unit at the Women's and Children's Hospital, Adelaide. Enrolled infants received a standardised nutrition protocol with emphasis on vitamin D supplementation. The main outcome measure was a comparison of the proportion of vitamin D-deficient infants (25(OH)D < 50 nmol/L) at birth versus 36 weeks post-menstrual age/discharge. RESULTS: Twenty-eight infants born between 30 and 36 weeks gestation were enrolled. The proportion of vitamin D-deficient infants decreased from initial to final measurement (32.1% vs. 7.1%, P = 0.016), whereas mean (standard deviation) 25(OH)D3 increased over the same period (58.4 (18.4) vs. 82.9 (29.2) nmol/L, P < 0.001). Mean vitamin D intake was 643.6 (285.3) IU/day. CONCLUSIONS: Current nutritional practices are effective in meeting recommendations regarding vitamin D intake and result in a lower proportion of deficient infants at 36 weeks post-menstrual age/discharge. |
Keywords: | neonatology nutrition preterm vitamin D |
Rights: | © 2015 The Authors |
DOI: | 10.1111/jpc.12847 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1046207 |
Published version: | http://dx.doi.org/10.1111/jpc.12847 |
Appears in Collections: | Aurora harvest 2 Paediatrics publications |
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