Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/89648
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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Sleebs, M. | - |
dc.contributor.author | Scanlon, D. | - |
dc.contributor.author | Karas, J. | - |
dc.contributor.author | Maharani, R. | - |
dc.contributor.author | Hughes, A. | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Journal of Organic Chemistry, 2011; 76(16):6686-6693 | - |
dc.identifier.issn | 0022-3263 | - |
dc.identifier.issn | 1520-6904 | - |
dc.identifier.uri | http://hdl.handle.net/2440/89648 | - |
dc.description | Publication Date (Web): July 8, 2011 | - |
dc.description.abstract | We report the solid-phase total synthesis of the antifungal highly modified cyclic depsipeptide petriellin A. The synthesis confirms earlier reports on the absolute configuration of the natural product. The solid-phase approach resulted in a protected linear precursor, which was cleaved from the solid support prior to cyclization and final deprotection. Use of advanced coupling agents for several hindered amides was a feature of the synthesis. The natural product was prepared in overall 5% yield. | - |
dc.description.statementofresponsibility | Marianne M. Sleebs, Denis Scanlon, John Karas, Rani Maharani, and Andrew B. Hughes | - |
dc.language.iso | en | - |
dc.publisher | American Chemical Society | - |
dc.rights | © 2011 American Chemical Society | - |
dc.source.uri | http://dx.doi.org/10.1021/jo201017w | - |
dc.subject | Amides | - |
dc.subject | Peptides, Cyclic | - |
dc.subject | Depsipeptides | - |
dc.subject | Antifungal Agents | - |
dc.subject | Molecular Structure | - |
dc.subject | Cyclization | - |
dc.title | Total synthesis of the antifungal depsipeptide petriellin A | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1021/jo201017w | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 7 Chemistry publications |
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