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https://hdl.handle.net/2440/90072
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Type: | Journal article |
Title: | Control of gene expression in the temperate coliphage 186. X. The cl repressor directly represses transcription of the late control gene B |
Author: | Dibbens, J.A. Gregory, S.L. Egan, J.B. |
Citation: | Molecular Microbiology, 1992; 6(18):2643-2650 |
Publisher: | Wiley |
Issue Date: | 1992 |
ISSN: | 0950-382X 1365-2958 |
Statement of Responsibility: | Justin A. Dibbens, Stephen L. Gregory and J. Barry Egan |
Abstract: | We have found that the repressor of 186 lytic transcription, CI, represses transcription of the late control gene B, with no involvement of the B protein Itself. In clone studies we showed that CI repressed transcription from the B promoter and that temperature inactivation of CIts led to B derepression. We conclude that CI repressor directly represses transcription of the Bgene and, with prophage induction, it is probable that the inactivation of the CI repressor not only derepresses early lytic transcription, but also derepresses B gene transcription, leading to the activation of transcription from the late promoters. |
Keywords: | Coliphages Transcription Factors Repressor Proteins Viral Proteins Virus Activation Transcription, Genetic Gene Expression Regulation, Viral Amino Acid Sequence Base Sequence Genes, Viral Molecular Sequence Data |
DOI: | 10.1111/j.1365-2958.1992.tb01441.x |
Published version: | http://dx.doi.org/10.1111/j.1365-2958.1992.tb01441.x |
Appears in Collections: | Aurora harvest 7 Genetics publications |
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