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https://hdl.handle.net/2440/90463
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Type: | Journal article |
Title: | Genome-wide survey of alternative splicing in sorghum bicolor |
Author: | Panahi, B. Abbaszadeh, B. Taghizadeghan, M. Ebrahimie, E. |
Citation: | Physiology and Molecular Biology of Plants, 2014; 20(3):323-329 |
Publisher: | Springer India |
Issue Date: | 2014 |
ISSN: | 0971-5894 0974-0430 |
Statement of Responsibility: | Bahman Panahi, Bahram Abbaszadeh, Mehdi Taghizadeghan, Esmaeil Ebrahimie |
Abstract: | Sorghum bicolor is a member of grass family which is an attractive model plant for genome study due to interesting genome features like low genome size. In this research, we performed comprehensive invest igation of Alternative Splicing and ontology aspects of genes those have undergone these events in sorghum bicolor . We used homology based alignments between gene rich transcripts, represented by tentative consensus (TC) transcript sequences, and genomic scaffolds to deduce the structure of genes and identify alternatively spliced transcripts in sorghum. Using homology mapping of assembled expressed sequence tags with genomics data, we identified 2,137 Alternative Splicing events in S. bicolor . Our study showed that complex events and intron retention are the main types of Alternative Splicing events in S. bicolor and highlights the prevalence of splicing site recognition for definition of introns in this plant. Annotations of the alternatively spliced genes revealed that they represent diverse biological process and molecular functions, suggesting a fundamental role for Alternative Splicing in affecti ng the development and physiology of S. bicolor . |
Keywords: | alternative splicing; ontology; complex events; intron retention |
Rights: | © Prof. H.S. Srivastava Foundation for Science and Society 2014 |
DOI: | 10.1007/s12298-014-0245-3 |
Published version: | http://dx.doi.org/10.1007/s12298-014-0245-3 |
Appears in Collections: | Aurora harvest 7 Molecular and Biomedical Science publications |
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