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https://hdl.handle.net/2440/113815
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Type: | Journal article |
Title: | Dysglycemia and glucose control during sepsis |
Author: | Plummer, M. Deane, A. |
Citation: | Clinics in Chest Medicine, 2016; 37(2):309-319 |
Publisher: | Elsevier |
Issue Date: | 2016 |
ISSN: | 0272-5231 1557-8216 |
Statement of Responsibility: | Mark P. Plummer, Adam M. Deane |
Abstract: | Sepsis predisposes to disordered metabolism and dysglycemia; the latter is a broad term that includes hyperglycemia, hypoglycemia, and glycemic variability. Dysglycemia is a marker of illness severity. Large randomized controlled trials have provided considerable insight into the optimal blood glucose targets for critically ill patients with sepsis. However, it may be that the pathophysiologic consequences of dysglycemia are dynamic throughout the course of a septic insult and also altered by premorbid glycemia. This review highlights the relevance of hyperglycemia, hypoglycemia, and glycemic variability in patients with sepsis with an emphasis on a rational approach to management. |
Keywords: | Sepsis; hyperglycemia; hypoglycaemia; glycemic variability |
Rights: | © 2016 Elsevier Inc. All rights reserved. |
DOI: | 10.1016/j.ccm.2016.01.010 |
Published version: | http://dx.doi.org/10.1016/j.ccm.2016.01.010 |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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