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https://hdl.handle.net/2440/124250
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Type: | Journal article |
Title: | Quality of life assessment in esophageal atresia patients: a systematic review focusing on long-gap esophageal atresia |
Author: | Tan Tanny, S.P. Comella, A. Hutson, J.M. Omari, T.I. Teague, W.J. King, S.K. |
Citation: | Journal of Pediatric Surgery, 2019; 54(12):2473-2478 |
Publisher: | Elsevier |
Issue Date: | 2019 |
ISSN: | 0022-3468 1531-5037 |
Statement of Responsibility: | Sharman P. Tan Tanny, Assia Comella, John M. Hutson, Taher I. Omari, Warwick J. Teague, Sebastian K. King |
Abstract: | Background: Children born with esophageal atresia (EA) have inherent abnormalities in esophageal motility which may impact upon patient and family Quality of Life (QoL). Currently, paucity of data exists for long-term outcomes of long-gap EA. We aimed to: (1) summarize QoL tools reported in the literature, focusing upon studies involving long-gap EA patients, and (2) compare QoL for long-gap versus non-long-gap EA patients. Method: We performed a systematic review of Cochrane Register of Controlled Trials, PubMed, EMBASE, and Ovid databases (January 1980-May 2018) in accordance with the PRISMA protocol. Result: Six studies were identified (536 patients total), and 419/536 (78%) patients completed QoL assessment. Response rates ranged from 29% to 100%. Median study size was 86 (range 8-159). Esophageal atresia type was described in 477 patients, and 74/477 (16%) were long-gap. Common assessment tools were Gastrointestinal Quality of Life Index and 36-Item Short-Form Health Survey. Compared with healthy individuals, long-gap EA patients suffered more gastrointestinal symptoms. There were no significant differences in QoL outcomes between long-gap and non-long-gap EA patients. Conclusion: Current literature suggests no significant difference in QoL outcomes between long-gap and non-long-gap EA patients. However, due to questionnaire variability and range of response rates, the data should be interpreted with care. Level of Evidence: Level II. |
Keywords: | Esophageal atresia; long-gap; quality of life; systematic review |
Rights: | Crown Copyright © 2019 Published by Elsevier Inc. All rights reserved. |
DOI: | 10.1016/j.jpedsurg.2019.08.040 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1168142 |
Published version: | http://dx.doi.org/10.1016/j.jpedsurg.2019.08.040 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
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