Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/139499
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Type: | Journal article |
Title: | Insights into the invasive diagnostic challenges of coronary artery vasospasm - A systematic review |
Author: | Rehan, R. Beltrame, J. Yong, A. |
Citation: | Journal of Cardiology, 2024; 83(1):8-16 |
Publisher: | Elsevier |
Issue Date: | 2024 |
ISSN: | 0914-5087 1876-4738 |
Statement of Responsibility: | Rajan Rehan, John Beltrame, Andy Yong |
Abstract: | Coronary provocation testing is an essential diagnostic procedure when evaluating vasospastic angina. Invasive methods using acetylcholine or ergonovine are considered the current gold standard. Despite efforts from global cardiovascular institutions, current protocols vary in dosage, administration time, and procedural approach. In addition, concerns over the specificity of findings and potential complications have limited routine uptake of this procedure in clinical practice. This systematic review evaluates current diagnostic protocols, focusing on invasive provocation testing. We included studies using intracoronary provocation testing with acetylcholine or ergonovine for the assessment of coronary artery vasospasm that detailed specific elements of the procedure (dosage, administration time, etc.) and included ≥50 patients. A total of 28 articles met strict inclusion criteria. Our review highlights the heterogeneity between current diagnostic protocols for invasive provocation testing. We believe standardization of a diagnostic protocol will encourage both current and future cardiologists to incorporate such procedures in the evaluation of variant angina. |
Keywords: | Acetylcholine Coronary artery vasospasm Ergonovine Intracoronary provocation testing Vasospastic angina |
Description: | Available online 3 August 2023 |
Rights: | © 2023 Japanese College of Cardiology. Published by Elsevier Ltd. This is an open access article under the CC BY-NCND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
DOI: | 10.1016/j.jjcc.2023.07.020 |
Grant ID: | NHMRC |
Published version: | http://dx.doi.org/10.1016/j.jjcc.2023.07.020 |
Appears in Collections: | Medicine publications |
Files in This Item:
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hdl_139499.pdf | Published version | 1.55 MB | Adobe PDF | View/Open |
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