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https://hdl.handle.net/2440/16937
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Type: | Journal article |
Title: | Is the mature endotoxin Cry1Ac from Bacillus thuringiensis inactivated by a coagulation reaction in the gut lumen of resistant, Helicoverpa armigera larvae? |
Author: | Ma, G. Roberts, H. Sarjan, M. Featherstone, N. Lahnstein, J. Akhurst, R. Schmidt, O. |
Citation: | Insect Biochemistry and Molecular Biology, 2005; 35(7):729-739 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2005 |
ISSN: | 0965-1748 1879-0240 |
Statement of Responsibility: | Gang Ma, Harry Roberts, Muhammad Sarjan, Nicki Featherstone, Jelle Lahnstein, Ray Akhurst and Otto Schmidt |
Abstract: | Bacillus thuringiensis endotoxins (Bt-toxins) are the most important biopesticides used in controlling insect pests and vectors of diseases. The emergence of widespread resistance to Bt in some insect species is a serious threat to agricultural production. Analysis of Bt-resistant and susceptible laboratory strains of Helicoverpa armigera revealed elevated immune responses involving increased melanization and the presence of a soluble toxin-binding glycoprotein in the hemolymph and gut lumen of the resistant strain. We propose a resistance mechanism against toxins based on a systemic immune-induction that can be transmitted to the next generation by a maternal effect. |
Keywords: | Lectin coagulation melanization maternal effect hexamerin bacillus thuringiensis endotoxin |
DOI: | 10.1016/j.ibmb.2005.02.011 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/390/description#description |
Published version: | http://dx.doi.org/10.1016/j.ibmb.2005.02.011 |
Appears in Collections: | Agriculture, Food and Wine publications Aurora harvest 6 |
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