Amifostine in the management of radiation-induced and chemo-induced mucositis

Abstract

Introduction Mucositis is a significant complication of cancer therapy, with important clinical and economic implications. In June 2005, the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society for Oral Oncology (MASCC/ISOO) conducted an evidence-based update review of the literature on mucositis. The goal of this literature review is to update previously published guidelines for the management of mucositis. Results This article reports the findings of the subgroup charged with reviewing the literature related to amifostine.