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https://hdl.handle.net/2440/46891
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Type: | Journal article |
Title: | Trends in five-year survival and risk of recurrent stroke after first-ever stroke in the Perth Community Stroke Study |
Author: | Hardie, K. Jamrozik, K. Hankey, G. Broadhurst, R. Anderson, C. |
Citation: | Cerebrovascular Diseases, 2005; 19(3):179-185 |
Publisher: | Karger |
Issue Date: | 2005 |
ISSN: | 1015-9770 1421-9786 |
Abstract: | <jats:p><i>Background:</i> Few studies provide information on trends in the long-term outcome of stroke. Weaimed to determine trends in survival and recurrent stroke, over 5 years after first-ever stroke, for 2 cohorts of patients enrolled in the Perth Community Stroke Study in 1989–90 and 1995–96. <i>Methods:</i> For 12-month periods beginning February 1989 and February 1995, all individuals with an acute stroke who were resident in a geographically-defined and representative region of Perth, Western Australia, were registered and followed-up prospectively 5 years after the index event. <i>Results:</i> The 5-year cumulative risk of death was 59% (95% confidence interval (CI) 53%, 65%) and 58% (95% CI 52%, 65%) for the 1989–90 and 1995–96 cohorts, respectively (p = 0.94). The 5-year cumulative risk of first recurrent stroke was 32% (95% CI 25%, 40%) and 23% (95% CI 16%, 30%) for the 1989–90 and 1995–96 cohorts, respectively (p = 0.07). <i>Conclusions:</i> Although no statistically significant improvement occurred in 5-year survival after first-ever stroke in Perth between 1989–90 and 1995–96, there was a statistically nonsignificant trend towards a smaller cumulative risk of recurrent stroke over 5 years after a first-ever stroke. Serial community-based studies of the incidence and outcome of stroke are an important means of monitoring the translation of proven preventive interventions to improvements in population health.</jats:p> |
Keywords: | Stroke Morbidity Trends Epidemiology Australia |
DOI: | 10.1159/000083253 |
Published version: | http://dx.doi.org/10.1159/000083253 |
Appears in Collections: | Aurora harvest 6 Medicine publications |
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