Browsing "Special Research Centre for the Molecular Genetics of Development (CMGD)" by Author Whitelaw, M.

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2002A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumorsAndersson, P.; McGuire, J.; Rubio, C.; Gradin, K.; Whitelaw, M.; Pettersson, S.; Hanberg, A.; Poellinger, L.
2000A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1a and the HIF-like factorLando, D.; Pongratz, I.; Poellinger, L.; Whitelaw, M.
2005Activity of hypoxia-inducible factor 2α is regulated by association with the NF-κB essential modulatorBracken, C.; Whitelaw, M.; Peet, D.
2002Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switchLando, D.; Peet, D.; Whelan, D.; Gorman, J.; Whitelaw, M.
2006Cell-specific regulation of hypoxia-inducible factor (HIF)-1α and HIF-2α stabilization and transactivation in a graded oxygen environmentBracken, C.; Fedele, A.; Karttunen, S.; Balrak, W.; Lisy, K.; Whitelaw, M.; Peet, D.
2004Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulatorsChapman-Smith, A.; Lutwyche, J.; Whitelaw, M.
2003Defining the role for XAP2 in stabilization of the dioxin receptorLees, M.; Peet, D.; Whitelaw, M.
2001Definition of a dioxin receptor mutant that is a constitutive activator of transcription - Delineation of overlapping repression and ligand binding functions within the PAS domainMcGuire, J.; Okamoto, K.; Whitelaw, M.; Tanaka, H.; Poellinger, L.
2002Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element - Cross-talk between basic helix-loop-helix/Per-Arnt-Sim homology transcription factorsWoods, S.; Whitelaw, M.
2002Effect of ARA9 on dioxin receptor mediated transcriptionLees, M.; Whitelaw, M.
2002FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factorLando, D.; Peet, D.; Gorman, J.; Whelan, D.; Whitelaw, M.; Bruick, R.
2002Mammalian two-hybrid assay showing redox control of HIF-like factorLando, D.; Peet, D.; Pongratz, I.; Whitelaw, M.
2006Novel DNA binding by a basic helix-loop-helix protein - The role of the dioxin receptor PAS domainChapman-Smith, A.; Whitelaw, M.
2004Oxygen-dependent asparagine hydroxylationPeet, D.; Lando, D.; Whelan, D.; Whitelaw, M.; Gorman, J.
2003Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylationLando, D.; Gorman, J.; Whitelaw, M.; Peet, D.
2005Phosphorylation inhibits DNA-binding of alternatively spliced aryl hydrocarbon receptor nuclear translocatorKewley, R.; Whitelaw, M.
2002Regulation of gene expression by the hypoxia-inducible factorsFedele, A.; Whitelaw, M.; Peet, D.
2004Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factorKarttunen, S.; Stojkoski, C.; Kewley, R.; Booker, G.; Whitelaw, M.; Peet, D.
2007The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factorsFurness, S.; Lees, M.; Whitelaw, M.
2003The hypoxia-inducible factors: key transcriptional regulators of hypoxic responsesBracken, C.; Whitelaw, M.; Peet, D.