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https://hdl.handle.net/2440/57218
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Type: | Journal article |
Title: | Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: implications for combination TKI therapy |
Author: | Hiwase, D. White, D. Zrim, S. Saunders, V. Vaz de Melo, J. Hughes, T. |
Citation: | Leukemia, 2010; 24(3):658-660 |
Publisher: | Nature Publishing Group |
Issue Date: | 2010 |
ISSN: | 0887-6924 1476-5551 |
Statement of Responsibility: | DK Hiwase, D White, S Zrim, V Saunders, J V Melo and T P Hughes |
Keywords: | K562 Cells Humans Pyrimidines Thiazoles Antineoplastic Combined Chemotherapy Protocols Protein Kinase Inhibitors Drug Synergism Leukemia, Myelogenous, Chronic, BCR-ABL Positive Dasatinib ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1 |
DOI: | 10.1038/leu.2009.242 |
Published version: | http://dx.doi.org/10.1038/leu.2009.242 |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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