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https://hdl.handle.net/2440/68417
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Type: | Journal article |
Title: | A 13-nation population survey of upper gastrointestinal symptoms: Prevalence of symptoms and socioeconomic factors |
Author: | Haag, S. Andrews, J. Gapasin, J. Gerken, G. Keller, A. Holtmann, G. |
Citation: | Alimentary Pharmacology and Therapeutics, 2011; 33(6):722-729 |
Publisher: | Blackwell Publishing Ltd |
Issue Date: | 2011 |
ISSN: | 0269-2813 1365-2036 |
Statement of Responsibility: | S. Haag, J. M. Andrews, J. Gapasin, G. Gerken, A. Keller & G. J. Holtmann |
Abstract: | Background: Previous data collected in separate studies using various different survey instruments have suggested some variability in the prevalence of symptoms between nations. However, there is a lack of studies which assess and compare the prevalence of upper gastrointestinal symptoms contemporaneously in various countries using a uniform, standardised method. Aim: To determine the prevalence of upper gastrointestinal (UGI) symptoms in 13 European countries, and the association between socioeconomic factors and symptoms using a standardised method. Methods: A representative age- and gender-stratified sample of 23 163 subjects (aged 18–69 years) was surveyed. Results: The prevalence of UGI symptoms was 38%. UGI symptoms were most prevalent in Hungary [45%, 95% confidence interval (CI): 42.2–48.4] and lowest in the Netherlands (24%, 95% CI: 21.0–26.2). UGI symptoms were more prevalent in women (39%, 95% CI: 38.4–39.6) vs. men (37%, 95% CI: 36.4–37.6). Heartburn (24%, 95% CI: 23.4–24.6) and acidic reflux (14%, 95% CI: 13.6–14.4) were most common. With age, the prevalence of UGI symptoms decreased (e.g. 18–29 years: 43%, 95% CI: 41.4–44.3 vs. 50–69 years: 33%, 95% CI: 32.3–34.4); in contrast, the frequency of symptom episodes/year increased with age (e.g. 18–29 years: 11.3 episodes per years, 95% CI: 10.5–12.1 vs. 50–69 years: 21.8, 95% CI: 20.7–22.9). Socioeconomic status as measured by gross domestic product was inversely associated with symptoms and in total, socioeconomic factors, gender, body mass index, smoking habits and alcohol consumption explained 83% of the variance of UGI symptoms. Conclusions: There are marked differences in the country specific prevalence of upper gastrointestinal complaints. Socioeconomic factors are closely associated with the prevalence of upper gastrointestinal symptoms. |
Keywords: | Humans Gastrointestinal Diseases Heartburn Epidemiologic Methods Age Distribution Sex Distribution Socioeconomic Factors Adolescent Adult Aged Middle Aged Income Europe Female Male Young Adult Global Health |
Rights: | © 2011 Blackwell Publishing Ltd. |
DOI: | 10.1111/j.1365-2036.2010.04564.x |
Published version: | http://dx.doi.org/10.1111/j.1365-2036.2010.04564.x |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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