Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/71797
Type: | Journal article |
Title: | Therapeutic hypothermia initiated in the pre-hospital setting: a meta-analysis |
Author: | Cullen, Deborah Augenstine, Dustin Kaper, LesLee Tinkham, Shawn Utz, Dawn |
Citation: | Advanced Emergency Nursing Journal, 2011; 33(4):314-321 |
Publisher: | Lippincott Williams & Wilkins |
Issue Date: | 2011 |
ISSN: | 1931-4485 |
School/Discipline: | The Joanna Briggs Institute |
Statement of Responsibility: | D. Cullen, D. Augenstine, L. Kaper, S. Tinkham and D. Utz |
Abstract: | After resuscitation of the cardiac arrest patient, reperfusion to the brain begins a cascade of events that may lead to permanent brain damage. Cooling suppresses the inflammatory response related to ischemia and metabolic demand, improving oxygen supply to anoxic areas. Until recently, cooling was only performed in the hospital setting. Recent studies have questioned whether initiating the cooling process immediately after resuscitation is beneficial in the pre-hospital setting. The primary purpose of this study was to examine the feasibility and safety of pre-hospital hypothermia via data extraction from randomized controlled trials and statistical meta-analysis. Studies included in this analysis did show a significant statistical difference with the ability to lower the body temperature when beginning pre-hospital cooling immediately, making it feasible to start therapeutic hypothermia in the pre-hospital setting. Further research is needed to determine neurological and discharge outcomes as the studies were not powered to determine statistical significance. |
Rights: | Copyright status unknown |
Description (link): | http://www.ncbi.nlm.nih.gov/pubmed/22075682 |
Appears in Collections: | Medicine publications |
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