Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/80753
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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Mijajlovic, M. | - |
dc.contributor.author | Wright, D. | - |
dc.contributor.author | Zivkovic, V. | - |
dc.contributor.author | Bi, J. | - |
dc.contributor.author | Biggs, M. | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Colloids and Surfaces B: Biointerfaces, 2013; 104:276-281 | - |
dc.identifier.issn | 0927-7765 | - |
dc.identifier.issn | 1873-4367 | - |
dc.identifier.uri | http://hdl.handle.net/2440/80753 | - |
dc.description.abstract | Lipid vesicles have received significant attention in areas ranging from pharmaceutical and biomedical engineering to novel materials and nanotechnology. Microfluidic-based synthesis of liposomes offers a number of advantages over the more traditional synthesis methods such as extrusion and sonication. One such microfluidic approach is microfluidic hydrodynamic focusing (MHF), which has been used to synthesize nanoparticles and vesicles of various lipids. We show here that this method can be utilized in synthesis of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) vesicles with controllable size. Since POPC is among the primary constituents of cellular membranes, this work is of direct applicability to modelling of biological systems and development of nano-containers with higher biologic compatibility for pharmaceutical and medical applications. | - |
dc.description.statementofresponsibility | M. Mijajlovic, D. Wright, V. Zivkovic, J.X. Bi, M.J. Biggs | - |
dc.language.iso | en | - |
dc.publisher | Elsevier Science BV | - |
dc.rights | Copyright © 2012 Elsevier B.V. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.colsurfb.2012.12.020 | - |
dc.subject | Artificial cells | - |
dc.subject | Drug delivery | - |
dc.subject | Liposomes | - |
dc.subject | Microfluidics | - |
dc.subject | Model biological systems | - |
dc.title | Microfluidic hydrodynamic focusing based synthesis of POPC liposomes for model biological systems | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.colsurfb.2012.12.020 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Bi, J. [0000-0001-7056-8572] | - |
Appears in Collections: | Aurora harvest Chemical Engineering publications |
Files in This Item:
File | Description | Size | Format | |
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hdl_80753.pdf | Accepted version | 822.83 kB | Adobe PDF | View/Open |
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