Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/87006
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Silica materials in drug delivery applications |
Author: | Simovic, S. Ghouchi-Eskandar, N. Sinn, A. Losic, D. Prestidge, C. |
Citation: | Current Drug Discovery Technologies, 2011; 8(3):250-268 |
Publisher: | Bentham Science Publishers |
Issue Date: | 2011 |
ISSN: | 1570-1638 1875-6220 |
Statement of Responsibility: | Spomenka Simovic, Nasrin Ghouchi-Eskandar, Aw Moom Sinn, Dusan Losic and Clive A. Prestidge |
Abstract: | In this review article we collect and analyse preparation, chemistry and properties of silica materials relevant for drug delivery applications. We review some of the most relevant milestones in the research of silica materials for implantable, oral, intravenous and dermal drug delivery systems. Preparation, chemistry and drug delivery characteristics of fumed silica nanoparticles (oral and dermal delivery route), silica xerogels (implant delivery), mesoporous silica materials (implant and oral delivery) and mesoporous silica spheres (intravenous delivery) with particular emphasis on their role in anticancer therapy and the design of stimuli responsive drug delivery systems are analysed. Recent progress in the research of silica materials for controlled drug delivery, namely, biocompatibility aspects, research on hybrid materials, anticancer and stimuli-responsive mesoporous silica materials are particularly emphasized. |
Keywords: | Animals Humans Neoplasms Silicon Dioxide Antineoplastic Agents Delayed-Action Preparations Drug Implants Drug Carriers Drug Delivery Systems Porosity Nanoparticles |
Rights: | Copyright status unknown |
DOI: | 10.2174/157016311796799026 |
Published version: | http://dx.doi.org/10.2174/157016311796799026 |
Appears in Collections: | Aurora harvest 7 Chemical Engineering publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.