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https://hdl.handle.net/2440/87706
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Type: | Journal article |
Title: | Dyspepsia and irritable bowel syndrome in China: a population-based endoscopy study of prevalence and impact |
Author: | Zhao, Y. Zou, D. Wang, R. Ma, X. Yan, X. Man, X. Gao, L. Fang, J. Yan, H. Kang, X. Yin, P. Hao, Y. Li, Q. Dent, J. Sung, J. Halling, K. Wernersson, B. Johansson, S. He, J. |
Citation: | Alimentary Pharmacology and Therapeutics, 2010; 32(4):562-572 |
Publisher: | Wiley |
Issue Date: | 2010 |
ISSN: | 0269-2813 1365-2036 |
Statement of Responsibility: | Y. Zhao, D. Zou, R. Wang, X. Ma, X. Yan, X. Man, L. Gao, J. Fang, H. Yan, X. Kang, P. Yin, Y. Hao, Q. Li, J. Dent, J. Sung, K. Halling, B. Wernersson, S. Johansson, and J. He |
Abstract: | Background: Dyspepsia and irritable bowel syndrome (IBS) are common in Western populations. Aim: To determine the epidemiology of dyspepsia and IBS in China. Methods: A representative sample of 18 000 adults from five regions of China were asked to complete the modified Rome II questionnaire; 20% were asked to complete the 36-item Short Form Health Survey (SF-36). Participants from Shanghai were invited to provide blood samples and undergo oesophagogastroduodenoscopy. Odds ratios (ORs) and 95% confidence intervals (CIs) were determined using a multivariate logistic regression model. Results: The survey was completed by 16 091 individuals (response rate: 89.4%). Overall, 387 participants (2.4%) had dyspepsia and 735 (4.6%) had IBS. All SF-36 dimension scores were at least five points lower in individuals with than without dyspepsia or IBS (P ≤ 0.001). In Shanghai, 1030 (32.7%) of the 3153 respondents agreed to endoscopy; neither dyspepsia nor IBS was found to be associated with reflux oesophagitis, peptic ulcer disease or Helicobacter pylori infection. Conclusions: Prevalence estimates for dyspepsia and IBS in China are lower than in Western populations. In China, dyspepsia or IBS symptoms are generally not associated with underlying organic disease. |
Keywords: | No keywords specified |
Rights: | © 2010 Blackwell Publishing Ltd. |
DOI: | 10.1111/j.1365-2036.2010.04376.x |
Published version: | http://dx.doi.org/10.1111/j.1365-2036.2010.04376.x |
Appears in Collections: | Aurora harvest 7 Medicine publications |
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