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https://hdl.handle.net/2440/99667
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dc.contributor.author | Parthiban, N. | - |
dc.contributor.author | Esterman, A. | - |
dc.contributor.author | Mahajan, R. | - |
dc.contributor.author | Twomey, D. | - |
dc.contributor.author | Pathak, R. | - |
dc.contributor.author | Lau, D. | - |
dc.contributor.author | Roberts-Thomson, K. | - |
dc.contributor.author | Young, G. | - |
dc.contributor.author | Sanders, P. | - |
dc.contributor.author | Ganesan, A. | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Journal of the American College of Cardiology, 2015; 65(24):2591-2600 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.issn | 1558-3597 | - |
dc.identifier.uri | http://hdl.handle.net/2440/99667 | - |
dc.description.abstract | BACKGROUND: Remote monitoring (RM) of implantable cardioverter-defibrillators (ICD) is an established technology integrated into clinical practice. One recent randomized controlled trial (RCT) and several large device database studies have demonstrated a powerful survival advantage for ICD patients undergoing RM compared with those receiving conventional in-office (IO) follow-up. OBJECTIVES: This study sought to conduct a systematic literature review and meta-analysis of RCTs comparing RM with IO follow-up. METHODS: Electronic databases and reference lists were searched for RCTs reporting clinical outcomes in ICD patients who did or did not undergo RM. Data were extracted from 9 RCTs, including 6,469 patients, 3,496 of whom were randomized to RM and 2,973 to IO follow-up. RESULTS: In the RCT setting, RM demonstrated clinical outcomes comparable with office follow-up in terms of all-cause mortality (odds ratio [OR]: 0.83; p = 0.285), cardiovascular mortality (OR: 0.66; p = 0.103), and hospitalization (OR: 0.83; p = 0.196). However, a reduction in all-cause mortality was noted in the 3 trials using home monitoring (OR: 0.65; p = 0.021) with daily verification of transmission. Although the odds of receiving any ICD shock were similar in RM and IO patients (OR: 1.05; p = 0.86), the odds of inappropriate shock were reduced in RM patients (OR: 0.55; p = 0.002). CONCLUSIONS: Meta-analysis of RCTs demonstrates that RM and IO follow-up showed comparable overall outcomes related to patient safety and survival, with a potential survival benefit in RCTs using daily transmission verification. RM benefits include more rapid clinical event detection and a reduction in inappropriate shocks. | - |
dc.description.statementofresponsibility | Nirmalatiban Parthiban, Adrian Esterman, Rajiv Mahajan, Darragh J. Twomey, Rajeev K. Pathak, Dennis H. Lau, Kurt C. Roberts-Thomson, Glenn D. Young, Prashanthan Sanders, Anand N. Ganesan | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.rights | © 2015 by the American College of Cardiology Foundation. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.jacc.2015.04.029 | - |
dc.subject | home monitoring | - |
dc.subject | mortality | - |
dc.subject | shock | - |
dc.subject | sudden cardiac death | - |
dc.title | Remote monitoring of implantable cardioverter-defibrillators: a systematic review and meta-analysis of clinical outcomes | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.jacc.2015.04.029 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Esterman, A. [0000-0001-7324-9171] | - |
dc.identifier.orcid | Mahajan, R. [0000-0003-3375-5568] | - |
dc.identifier.orcid | Pathak, R. [0000-0002-7391-6867] | - |
dc.identifier.orcid | Lau, D. [0000-0001-7753-1318] | - |
dc.identifier.orcid | Sanders, P. [0000-0003-3803-8429] | - |
Appears in Collections: | Aurora harvest 7 Medicine publications |
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